منابع مشابه
Role of Coagulation Factors in Diabetic Retinopathy
The role of coagulation factors in diabetic retinopathy was studied in non-insulin-dependent diabetic patients. Patients with retionopathy had higher levels of beta thromboglobulin, von Willebrand factor and fibrinogen levels compared to diabetics without retinopathy and controls. Serum magnesium levels were not significantly different between the groups studied. The role of coagulation factors...
متن کاملRole of Inflammation in Diabetic Retinopathy.
Diabetic retinopathy is a common complication of diabetes and remains the leading cause of blindness among the working-age population. For decades, diabetic retinopathy was considered only a microvascular complication, but the retinal microvasculature is intimately associated with and governed by neurons and glia, which are affected even prior to clinically detectable vascular lesions. While pr...
متن کاملRole of FAM18B in diabetic retinopathy
PURPOSE Genome-wide association studies have suggested an association between a previously uncharacterized gene, FAM18B, and diabetic retinopathy. This study explores the role of FAM18B in diabetic retinopathy. An improved understanding of FAM18B could yield important insights into the pathogenesis of this sight-threatening complication of diabetes mellitus. METHODS Postmortem human eyes were...
متن کاملThe Role of Microglia in Diabetic Retinopathy
There is growing evidence that chronic inflammation plays a role in both the development and progression of diabetic retinopathy. There is also evidence that molecules produced as a result of hyperglycemia can activate microglia. However the exact contribution of microglia, the resident immune cells of the central nervous system, to retinal tissue damage during diabetes remains unclear. Current...
متن کاملEffects of quercetin on the expression of MCP-1, MMP-9 and VEGF in rats with diabetic retinopathy
Diabetic retinopathy, a severe complication of diabetes, is the leading cause of blindness in the developed world. This study investigated the effects of quercetin on levels of monocyte chemoattractant protein-1 (MCP-1), matrix metalloproteinase-9 (MMP-9) and vascular endothelial growth factor (VEGF) in serum of rats with diabetic retinopathy, and explored the functional mechanisms of quercetin...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2020
ISSN: 2250-1177
DOI: 10.22270/jddt.v10i6-s.4635